Product Overview
Product name:(+)-Borneol / Borneol
CAS Number: 464-43-7
Molecular formula: C₁₀H₁₈O
Structure:
Appearance: Colorless or white semi-transparent crystals
Smell: It has a unique camphor-like refreshing aroma
Solubility: Readily soluble in ethanol and ether, slightly soluble in water
(+)-Borneol, also known as Natural borneol, is extracted from the fresh branches and leaves of the Camphor tree, a plant of the Lauraceae family, through physical distillation. It looks like mica and is as white as ice and snow. It is renowned as "botanical gold" and "king of medicines", and has extremely high medicinal value and health benefits.
Production
There are mainly three production processes for (+)-Borneol.
Plant extraction.
The processed products of (+)-Borneol resin from the Borneol family plant or the crystals obtained after water distillation and sublimation of tree trunks and branches, followed by cooling, are (+)-Borneol. At present, extraction from plants remains the mainstream method for the production of natural (+)-Borneol.
Chemical synthesis
ene in turpentine is used as the raw material. Through the addition reaction of organic acids to form esters, and then through saponification reaction to produce synthetic borneol. The relative content of (+)-Borneol and its isomers in synthetic borneol is affected by the reaction conditions. The reaction is difficult to control, prone to explosion, with low yield and high content of toxic isorotagneol in the product.
Biosynthesis method
In recent years, people have begun to utilize microorganisms or enzymes for the biocatalytic synthesis or modification of natural products. Biocatalysis has attracted attention due to its simple process, mild conditions, convenient operation, few side reactions and by-products, and the ability to obtain compounds with a single stereoconfiguration.
BrightGene Health uses biological methods to produce (+)-Borneol, achieving a high purity of 99.5%, while keeping the total impurity within 0.2% and reducing the output of toxic isomers.
Functions
Medical
(+)-Borneol has medicinal effects such as analgesia, anti-inflammation, anti-bacterial, protection of the cardiovascular and cerebrovascular system, prevention of thrombosis, promotion of drug passage through the blood-brain barrier, and anti-protection of the central nervous system. It can enhance osmotic activity, repair and protect DNA cell damage, treat skin trauma, promote drug absorption, and improve the permeability of the blood vessel wall. Open the blood-cerebrospinal fluid barrier and the blood-brain barrier, inhibit the metabolic rate of shared drugs in the organism, and improve bioavailability. In modern times, it is mostly used for acute coma, acute encephalopathy, epilepsy, sequelae of concussion, etc., which belong to the condition of "closure syndrome and coma". It is commonly used externally for acute conjunctivitis, acute tonsillitis, stomatitis, as well as for abscesses and burns, etc.
Flavor & Fragrance
(+)-Borneol, as a raw material for spices and essences, can be safely used externally. When perfuming, a small amount of natural borneol is usually used in combination with lavender, myrtle and gulong, etc. The use of (+)-Borneol in soap flavoring can enhance the refreshing smell effect. In addition, (+)-Borneol is often used together with frankincense in the production of incense essence. When preparing lavender oil, (+)-Borneol must be added. Due to its anti-inflammatory and sterilizing effects, it is often used together with peppermint oil in products such as tooth powder, talcum powder and clam oil odor spray. At the same time, its fragrant effect is also utilized. The traditional Chinese ink manufacturing process requires the addition of (+)-Borneol to give the calligraphy with a brush a lasting luster and give off the "ink fragrance". When burned,(+)-Borneol gives off a rich and mysterious fragrant smell. Therefore, in some Buddhist countries, (+)-Borneol is widely used as a burnt item in religious ceremonies or funerals. (+)-Borneol can be used as a fixative for high-end perfumes and is also employed in the formulation of high-end perfumes. In terms of food flavoring, trace amounts of (+)-Borneol can be applied to the flavoring of nuts, chewing gum and spicy foods.
Cosmetic
(+)-Borneol itself can be absorbed through the skin, and enhanced skin hydration can also promote the penetration of (+)-Borneol. The effect of (+)-Borneol in promoting transdermal absorption mainly lies in the stratum corneum, which can enhance the reservoir effect of intact skin and its exfoliated skin. (+)-Borneol can have anti-inflammatory and analgesic effects on the skin.