Extraction method of resveratrol

Solvent extraction method
Solvent extraction is one of the most widely used extraction methods both domestically and internationally. The commonly used solvent extraction methods mainly include three types: percolation method, extraction method, and reflux method. The commonly used solvents for reflux extraction of resveratrol include methanol, ethanol, acetone, ethyl acetate, etc. Among them, 60% to 90% ethanol aqueous solution is the most commonly used for reflux extraction of resveratrol from the original plant. Other solvents are rarely used due to low efficiency or relatively high toxicity.
Enzymatic extraction
Resveratrol exists in many plants in the form of resveratrol glycosides, which can be enzymatically hydrolyzed into resveratrol and then extracted as free resveratrol. This method can achieve higher yields, so some researchers have used enzymatic hydrolysis to extract resveratrol. There are three sources of enzymes in enzymatic extraction: using plant derived enzymes, adding external enzymes, and producing enzymes through microbial inoculation.
Microwave extraction
Microwave extraction is a method in which plant cells absorb microwave energy in a microwave field, causing a rapid increase in temperature, expansion, and rupture, which facilitates the extraction of active ingredients from plants. This method is commonly used in laboratory research.
Supercritical carbon dioxide extraction
Supercritical CO2 extraction is a process of extracting or separating certain components from a mixture using CO2 fluid in a supercritical state as a solvent. Supercritical CO2 is characterized by stable properties, non toxicity, non polluting the environment, strong permeability and solubility, as well as good transferability and fluidity.