Product Overview
Product Name: 4-Hexylresorcinol
CAS No.: 18979-61-8
Formula:C10H14O2
Structure:
Application: Cosmetics, whitening
It is well known that the core cause of skin tanning and the formation of spots is the deposition of melanin. The generally recognized and more effective approach is to directly inhibit the source of melanin production, namely tyrosinase, temporarily depriving melanocytes of their ability to produce melanin. Then, by supplementing with some components that interfere with melanin transport, precise and efficient whitening and fading of spots can be achieved.
At present, there are several inhibitors of tyrosinase, such as the well-known 377 and kojic acid. 4-Hexylresorcinol has emerged as a rising star in terms of whitening effects in recent years.
4-Hexylresorcinol, commonly known as 577, is hailed as the "second strongest whitening ingredient on the earth". As early as 1998, POLA Company registered it as the whitening ingredient Rucinol.
It belongs to small molecule compounds, which can penetrate into the basal layer of the skin, inhibit the production and transfer of melanin, enhance the degradation of tyrosinase, and decompose and eliminate the originally deposited melanin.
Features
【The speed of fading spots is fast, and significant improvement can be seen in human efficacy experiments within 8 weeks】
A small-sample trial published in the Journal of the European Society of Dermatology and Venereology investigated the efficacy of 577 in actual human
use:
577 has already shown a significant effect in fading spots after being used for 8 weeks.
Meanwhile, in the in vitro human tyrosinase test, 4-butylresorcinol had the strongest inhibitory effect on tyrosinase, being 5 times that of hexylresorcinol, 6 times that of phenethyl resorcinol (377), 25 times that of kojic acid, 325 times that of arbutin, and 220 times that of hydroquinone.
【It has a high efficiency in fading spots and shows remarkable effects even at a low concentration (0.3%)】
Another human test study pointed out that 52 subjects with an average age of around 38 and chloasma all saw significant improvement in their skin pigmentation after using a cream containing 0.3% 577 for 8 consecutive weeks.
