Introduction
Borneol, a bioactive bicyclic monoterpenoid alcohol (C₁₀H₁₈O), is a key therapeutic component in traditional medicine with multifaceted pharmacological actions. As a small lipophilic molecule, it rapidly absorbs through the gastrointestinal tract and exhibits unique membrane-penetrating properties that enhance drug delivery across biological barriers.
Core Mechanisms of Action:
Blood-Brain Barrier Modulation:
Increases BBB permeability by inhibiting P-glycoprotein (P-gp) activity, reducing drug efflux and elevating cerebral drug concentrations (e.g., enhances cisplatin distribution in glioblastoma models).
Transdermal/Tissue Absorption Promotion:
Disrupts stratum corneum structure to facilitate skin penetration.
Accelerates nasal/small intestinal mucosal absorption and shortens time-to-peak plasma concentration.
Improves corneal permeability for ophthalmic formulations.
This multifunctional compound bridges traditional medicine and modern drug delivery technology, with ongoing studies expanding its therapeutic potential. Regulatory status varies by region for clinical applications.
Borneol Solid 99%:Delivers high-purity Borneol.
Borneol
Borneol can be used in:
Pharmaceutical
Borneol is a key bioactive compound in traditional medicine, valued for its anti-inflammatory, analgesic, and neuroprotective effects. It enhances drug absorption and is used in emergency formulas (e.g., Angong Niuhuang Wan) and topical treatments for pain and infections.
Dietary supplement
In wellness products, Borneol may support relaxation and cognitive function through aromatherapy, while its antioxidant properties contribute to anti-aging formulations. Also, it's often used in blends for digestive or respiratory comfort.
Fragrance & Flavor
With a fresh, camphor-like aroma, Borneol is a premium ingredient in luxury perfumes and aromatherapy products. It acts as a fixative to prolong scent longevity and adds a cooling sensation to oral care (e.g., toothpaste) and cosmetics.
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