Main Function 
Sterility 
Endotoxin 
Concentration 
Appearance 
Production Process Product introduction
Placental exosomes are small membrane-bound extracellular vesicles released by the placenta during pregnancy. They contain a variety of biomolecules, including lipids, proteins, and nucleic acids, which can potentially be biomarkers of maternal diseases.The production process of our Bovine Placental Exosomes is 3D Cell culture.
Efficacy Experiment
Performance of placental exosomes in whitening
Using a 3D human skin model, UVB was used to induce melanin expression, kojic acid was used as a positive reference, and placental exosomes were administered to detect melanin expression.
Results
|
Blank |
Negative Control |
Positive Control |
Group 1 Smear |
Group 2 Injection |
|
|
P57.36 |
40.92 |
51 |
51.31 |
53.51 |
|
|
56.29 |
41.58 |
56.21 |
53.87 |
54.56 |
|
|
54.83 |
39.69 |
52.97 |
52.15 |
52.66 |
|
|
Mean+SD |
56.16±1.27 |
40.73±0.96 |
53.39±2.63 |
52.443±1.30 |
53.58±0.95 |
|
Blank |
Negative Control |
Positive Control |
Group 1 Smear |
Group 2 Injection |
|
|
11.84 |
14.43 |
13.17 |
11.47 |
12.73 |
|
|
12.55 |
14.66 |
12.95 |
14.10 |
12.21 |
|
|
10.91 |
14.25 |
12.65 |
12.99 |
12.47 |
|
|
Mean+SD |
11.77±0.82 |
14.45±0.20 |
12.93±0.26 |
12.85±1.32 |
12.47±0.26 |
Conclusion
In the human skin cell model irradiated by UV: compared with the untreated negative group, the L* value of the exosome smear group decreased by 20%, and the melanin content decreased by 13.6%; compared with the untreated negative group, the L* value of the exosome smear group decreased by 22.9%, and the melanin content decreased by 16.9%.
Standard Precautions
■ Recommended pH: 6.0-8.0
■ Storage Condition: -20℃
■ Packaging: Lyophilized powder, customized package.
Advantages of Our Company's Exosomes
Effective exosomes dose: 107~108 particles/ml
Products can be customized: 20 million cells from one biopsy, personal cell bank
High yield: 1011exosomes per million cells
Low cost: Weeks of cell culture
Safety: High biocompatibility and low-immunogenicity
Stability: Can be lyophilized for long term storage and transportation at room temperature.
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