3D Human Fibroblast Exosomes

Product Introduction

Exsomes are a type of extracellular vesicles and are naturally secreted lipid bilayer nanoparticles by cells. Exsomes are 30-150 nm in diameter and contain constituents (proteins, RNA) of parent cells and can mediate cell-cell interaction, affect cell function and behavior.Our 3D Human Fibroblast Exosomes uses 3D Cell culture.

[3D Cell Spheroids derived esosomes (3D-EXO) in anti-skin aging]:

Along with intrinsic aging (passage) and extrinsic aging (UVB) on human dermal fibroblasts (HDF), both the cells and the secreted exosomes show enhanced senescence phenotype and reduced collagen-producing ability. Suspended spheroid culture regains the regeneration ability and the collagen producing ability of HDF.

3D cell derived exosomes have more cytokines that contribute to angiogenesis and injury repairment process. 3D cell derived exosomes have miRNAs that contribute to collagen synthesis and anti-inflammation process.

Standard Precautions

 

■ Recommended pH: 6-8
■ Storage Condition: -20℃
■ Packaging: Lyophilized powder, customized package.

Advantages of Our Company's Exosomes

 

Effective exosomes dose: 10⁷~10⁸ particles/ml

Products can be customized: 20 million cells from one biopsy, personal cell bank

 

High yield: 10¹¹exosomes per million cells

Low cost: Weeks of cell culture

 

Safety: High biocompatibility and low-immunogenicity

 

Stability: Can be lyophilized for long term storage and transportation at room temperature.

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